Human herpesvirus-6 : general virology, epidemiology and clinical pathology /

The most comprehensive review available of all aspects of HHV-6 combining basic and clinical science.

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Bibliographic Details
Other Authors: Krueger, G. R. F., Ablashi, D. V. (Dharam V.)
Format: Electronic eBook
Language:English
Published: Amsterdam ; Boston : Elsevier, ©2006.
Edition:2nd ed.
Series:Perspectives in medical virology ; v. 12.
Subjects:
Online Access: Full text (Emmanuel users only)

MARC

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245 0 0 |a Human herpesvirus-6 :  |b general virology, epidemiology and clinical pathology /  |c editors, Gerhard Krueger, Dharam Ablashi. 
250 |a 2nd ed. 
260 |a Amsterdam ;  |a Boston :  |b Elsevier,  |c ©2006. 
300 |a 1 online resource (xvi, 376 pages) :  |b illustrations (some color). 
336 |a text  |b txt  |2 rdacontent 
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490 1 |a Perspectives in medical virology,  |x 0168-7069 ;  |v v. 12 
500 |a Ablashi's name appears first on the earlier edition. 
504 |a Includes bibliographical references and index. 
505 0 0 |t Foreword /  |r Robert C. Gallo --  |t Foreword /  |r Ronald Glaser, Marshall V. Williams --  |t Preface /  |r Gerhard R.F. Krueger, Dharam V. Ablashi --  |t Discovery and Classification of Human Herpesvirus-6 (HHV-6) /  |r Dharam V. Ablashi --  |t Ultrastructure and Assembly of Human Herpesvirus-6 (HHV-6) /  |r Z. Hong Zhou, James K. Stoops, Gerhard R.F. Krueger --  |t HHV-6 Genome: Similar and Different /  |r U.A. Gompels, F.C. Kasolo --  |t Proteins of HHV-6 /  |r Yasuko Mori --  |t Biological Features of HHV-6 /  |r Lorenzo Dagna, Fabio Santoro, Paolo Lusso --  |t Strain Variants of HHV-6 /  |r Dharam V. Ablashi --  |t Serologic Testing for Acute and Chronic Infection /  |r Henri Agut, Agnes Gautheret-Dejean --  |t Molecular Testing for HHV-6 Infection /  |r Stephen Dewhurst, Birgit Bradel-Tretheway --  |t Epidemiology of HHV6 /  |r Caroline Breese Hall --  |t Pathologic Features of HHV-6 Disease /  |r Gerhard R.F. Krueger, Brigitte Schneider --  |t Systemic Reactions to HHV-6 Infection /  |r Vincent Descamps, Emmanuel Mahe, Sylvie Ranger-Rogez --  |t HHV-6 and the Integument /  |r Tetsushi Yoshikawa --  |t HHV-6 and the Respiratory System /  |r Sebastian M. Schmidt, Helga Wiersbitzky, Siegfried K.W. Wiersbitzky --  |t HHV-6 and the Lympho-Hematopoietic System /  |r Sylvie Ranger-Rogez, Aurelie Lacroix, François Denis, Dominique Bordessoule --  |t Human Herpesvirus-6 and the Cellular Immune System /  |r Judith A. Britz --  |t HHV-6 and the Central Nervous System /  |r Samantha S. Soldan, Andrew D. Goodman, Steven Jacobson --  |t HHV-6 and the Cardiovascular System /  |r Satoki Fukae, Naoto Ashizawa --  |t HHV-6 in Cardiovascular Pathology /  |r L. Maximilian Buja --  |t HHV-6, the Liver and the Gastrointestinal Tract /  |r Tetsushi Yoshikawa --  |t HHV-6 in Chronic Fatigue Syndrome /  |r Daniel Peterson, Lisa Atwell --  |t HHV-6 and HIV-1 Infection /  |r Paolo Lusso --  |t Human Herpesvirus-6 Infection in Solid Organ and Stem Cell Transplant Recipients /  |r P. Ljungman, N. Singh --  |t Therapeutic Approaches to HHV-6 Infection /  |r Lieve Naesens, Leen De Bolle, Erik De Clercq --  |t Animal Models /  |r Claude P. Genain --  |t Computational Simulation of HHV-6 Infection /  |r Guanyu Wang, Gerhard R.F. Krueger --  |t Experimental Therapeutic Approaches. 
505 0 |a Cover -- Contents -- Foreword by Robert Gallo -- Foreword by Ronald Glaser and Marshall Williams -- Preface -- Part I: General Virology -- Discovery and Classification of Human Herpesvirus-6 (HHV-6) -- Discovery -- Nomenclature and classification -- References -- Ultrastructure and Assembly of Human Herpesvirus-6 (HHV-6) -- Introduction -- Herpesvirus-6 assembly and maturation -- Three-dimensional structure of HHV-6 capsid -- Comparision of the HHV-6 cappsid structure with those of other human herpesviruses -- Conclusion -- References -- HHV-6 Genome: Similar and Different -- Genome classification and biology -- Genomes, cellular tropism and laboratory culture -- Genome structure and repetitive sequence -- Genome rearrangements and relationship to other herpesviruses -- Genome composition and general molecular biology -- Herpesvirus conserved and HHV-6-specific genes -- Genomes and HHV-6 strains -- Acknowledgements -- References -- Proteins of HHV-6 -- Introduction -- IE proteins -- U16/U17 -- U53, proteinase -- U69, kinase -- Cellular homologues -- U94, AAV-2 rep homologue -- Envelope glycoproteins -- U39, gB -- U48 and U82, gH and gL -- U100, gQ -- U47, gO -- U11 -- U14 -- U27 -- Perspective -- References -- Biological Features of HHV-6 -- Introduction -- HHV-6 cellular receptor -- Species specificity -- Cellular tropism of HHV-6 -- Biological effects of HHV-6 on the host cell -- References -- Part II: Diagnosis and Epidemiology -- Strain Variants of HHV-6 -- Introduction -- Epidemiology -- Molecular biology -- Biological aspects of variants A and B -- Reactivity of monoclonal antibodies to HHV-6 variants A and B -- Disease associations of HHV-6A and -6B variants -- Concluding remarks -- References -- Serologic Testing for Acute and Chronic Infection -- Introduction -- Serologic assays -- Serologic findings -- Pending questions and perspectives -- Acknowledgments -- References -- Molecular Testing for HHV-6 Infection -- Introduction -- Primary infection: characteristics and diagnostic considerations -- PCR analysis of cell-free body fluids -- Reverse transcription PCR analysis -- Quantitative PCR analysis of HHV-6 DNA in PBMC or blood -- Detection of virus variants -- Other assay approaches -- Future assay methods -- PCR-based assays: general considerations and molecular underpinnings -- Commercially available tests -- General considerations for current molecular assays -- References -- Epidemiology of HHV6 -- The epidemiology of roseola from historical observations -- Seroepidemiologic studies of HHV6 infection -- Acquisition of HHV6 infection during childhood -- Acquisition of HHV6 infection according to variant -- Factors affecting acquisition of HHV6 infection -- Mode of transmission -- Incubation period -- Summary -- References -- Part III: Clinical Pathology -- Pathologic Features of HHV-6 Disease -- Introduction -- Cell and tissue tropism and strain differences -- General cellular pathology of HHV-6 infection -- Primary infection -- Reactivation and endogenous reinfection -- Conclusions -- References -- Systemic Reactions to HHV & 
520 |a The most comprehensive review available of all aspects of HHV-6 combining basic and clinical science. 
546 |a English. 
588 0 |a Print version record. 
650 0 |a Human herpesvirus-6. 
650 0 |a Human herpesvirus-6 infections. 
650 0 |a Herpesvirus diseases. 
650 1 2 |a Herpesviridae Infections 
650 1 2 |a Herpesvirus 6, Human 
655 7 |a Academic theses.  |2 lcgft 
700 1 |a Krueger, G. R. F. 
700 1 |a Ablashi, D. V.  |q (Dharam V.)  |1 https://id.oclc.org/worldcat/entity/E39PBJwttkWfm6b8DPTB4RVXBP 
758 |i has work:  |a Human herpesvirus-6 (Text)  |1 https://id.oclc.org/worldcat/entity/E39PCFQCW4BvY8kGR4mrqcQQMd  |4 https://id.oclc.org/worldcat/ontology/hasWork 
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