Q Fever /
Information on the changing epidemiology and expanding nosological range of Q fever in humans has gained much attention in the past decade. Q fever is a zoonotic disease caused by the highly infectious pathogen Coxiella burnetii and has global distribution with important health, social and economic...
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| Main Author: | |
|---|---|
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Gistrup, Denmark :
River Publishers,
[2017]
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| Series: | River Publishers series in research and business chronicles: biotechnology and medicine ;
volume 8. |
| Subjects: | |
| Online Access: |
Full text (Emmanuel users only) |
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| 100 | 1 | |a Martinov, Svetoslav P., |e author. | |
| 245 | 1 | 0 | |a Q Fever / |c Svetoslav P. Martinov, National Diagnostic and Research Veterinary Medical Institute -- Sofia, Bulgaria. |
| 264 | 1 | |a Gistrup, Denmark : |b River Publishers, |c [2017] | |
| 300 | |a 1 online resource (xxvi, 317 pages) : |b illustrations | ||
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| 490 | 1 | |a River Publishers Series in Research and Business Chronicles: Biotechnology and Medicine ; |v volume 8 | |
| 504 | |a Includes bibliographical references (pages 261-309) and index. | ||
| 505 | 0 | |a Preface xi -- List of Figures xiii -- List of Tables xxi -- List of Abbreviations xxv -- Introduction 1 -- 1 Historical Notes 5 -- 2 Etiology and Taxonomy 9 -- 3 Morphological Features, Development Cycle, and Interaction with Cells 13 -- 4 Ultrastructure of Coxiella burnetii and Electron Microscopic Diagnosis of Q Fever 17 -- 4.1 Light Microscopic Morphology of C. burnetii 17 -- 4.2 Ultrastructure of the Agent and Electron Microscopic Diagnosis of the Disease 20 -- 4.2.1 Placentas in Abortions and Births of Dead and Unviable Offspring 20 -- 4.2.2 Blood 24 -- 4.2.3 Chicken Embryos 28 -- 4.2.4 White Mice 29 -- 4.2.5 Guinea Pigs 32 -- 5 Isolation and Cultivation of Coxiella burnetii 39 -- 5.1 Strains Isolated from Sheep 42 -- 5.1.1 Abortions, Stillbirths, and Births to Non-viable Offspring 42 -- 5.1.2 Pneumonia in Sheep 47 -- 5.1.3 Mastitis in Sheep 48 -- 5.1.4 Latent Coxiellosis in Sheep 50 -- 5.2 Strains Isolated from Goats 50 -- 5.2.1 Abortions, Stillbirths, and Births to Non-viable Offspring 50 -- 5.2.2 Pneumonia in Goats 51 -- 5.2.3 Mastitis in Goats 51 -- 5.2.4 Isolation of C. burnetii from Blood in Goat Herds with Active Q Fever 57 -- 5.2.5 Latent Coxiellosis in Goats 57 -- 5.3 Strains Isolated from Cattle 57 -- 5.3.1 Abortions, Stillbirths, and Births to Non-viable Calves 57 -- 5.3.2 Pneumonia in Calves 58 -- 5.3.3 Mastitis in Cows 58 -- 5.3.4 Metritis and Endometritis 59 -- 5.3.5 Coxiella burnetii Isolation from the Blood of Cattle in Active Foci of Q Fever 61 -- 5.3.6 Isolation of C. burnetii from Wild Animal Species and Arthropods 61 -- 6 Virulence and Pathogenicity 71 -- 7 Antigens and Phase Variability 75 -- 8 Serology 77 -- 8.1 Serological Reactions 77 -- 8.2 Serological Test's Examinations 80 -- 8.2.1 Serological Data for the State of Agricultural Foci of Q Fever in Bulgaria 80 -- 8.3 Serological Status of the Infection Caused by Coxiella burnetii among Domestic Animals During the Epidemic of Q Fever in Humans in Etropole-2002 -- 83 -- 8.4 Serological Status of Infection with Coxiella burnetii among Domestic Animals During the Epidemic of Q Fever in Humans in the Region of Botevgrad-2004. | |
| 505 | 8 | |a 10 Clinical Picture 155 -- 10.1 Clinical Course of Q Fever in Animals 155 -- 10.2 Clinical Observations in Sheep 157 -- 10.2.1 Latent Form 157 -- 10.2.2 Abortions, Premature Births, Stillbirths, and Not Viable Lambs 158 -- 10.2.3 Pneumonias in Sheep 159 -- 10.2.4 Flu-Like Form in Sheep 162 -- 10.2.5 Mastitis in Sheep 162 -- 10.3 Clinical Observations in Goats 163 -- 10.3.1 Latent Form 163 -- 10.3.2 Abortion in Goats, Premature Births, Stillborn, and Non-viable Offsprings 164 -- 10.3.3 Respiratory Form in Goats 165 -- 10.3.4 Flu-Like Form in Goats 165 -- 10.3.5 Mastitis in Goats 166 -- 10.4 Clinical Observations in Cattle 166 -- 10.4.1 Latent Form 166 -- 10.4.2 Abortions in Cows, Premature Births, Stillborn, and Non-viable Calves 167 -- 10.4.3 Clinical Signs of the Dry Cows after Experimental Infection 168 -- 10.4.4 Pneumonias in Calves 169 -- 10.4.5 Endometritis, Metritis, and Infertility 169 -- 10.4.6 Mastitis in Cows 171 -- 10.4.7 Syndrome of Prolonged Reduction of Milk Production 172 -- 10.4.8 Clinical Signs in Some Laboratory Animals 172 -- 10.4.9 Analysis of the Clinical Data in Animals 176 -- 10.4.10 Clinical Course of Q Fever in Humans 181 -- 11 Pathogenesis and Pathological Morphology 185 -- 11.1 Pathomorphological Investigations in Domestic Ruminants with Etiologically Proven Q Fever 189 -- 11.1.1 Macroscopic Picture 189 -- 11.1.2 Microscopic Picture 191 -- 11.2 Pathomorphological Investigations in Some Laboratory Animals with Etiologically Proven Q Fever 196 -- 11.2.1 Macroscopic Picture 196 -- 11.2.2 Microscopic Picture in Rabbits 198 -- 12 Epizootiology and Epidemiology 205 -- 12.1 State of the Natural Foci of Q Fever in Bulgaria 210 -- 12.1.1 Ticks 210 -- 12.2 Wild Mammals and Birds 214 -- 12.3 Agricultural Foci of Q Fever in Bulgaria 217 -- 12.3.1 General Characteristics 217 -- 12.4 Internal Structure of the Agricultural Foci 218 -- 12.5 Categories of Animals in the Agricultural Foci 219 -- 12.6 Etiologically Proven Clinical Forms of Q Fever in the AF 219. | |
| 505 | 8 | |a 12.7 Autonomous Circulation Circle and Cyclical Reproduction of the Infection with C. burnetii in the Agricultural Foci 219 -- 12.8 Activity of Agricultural Foci and Epidemics of Q Fever in Humans 221 -- 12.9 Relationships between Natural and Agricultural Foci of Q Fever 221 -- 12.10 Epidemiological Particularities in Humans 225 -- 12.11 Analysis of Epizootiological and Epidemiological Data 231 -- 13 Sensitivity to Antibiotics and Treatment 239 -- 13.1 Sensitivity of C. burnetii to Certain Antibiotics Depending on Its Phase State 244 -- 14 Prevention and Control 251 -- 14.1 System for Monitoring, Prevention, and Fight against Q Fever 255 -- 14.1.1 General Preventive Measures and Epidemiological Control 255 -- 14.1.2 Measures to Combat the Disease 258 -- Bibliography 261 -- Index 311 -- About the Author 317. | |
| 520 | |a Information on the changing epidemiology and expanding nosological range of Q fever in humans has gained much attention in the past decade. Q fever is a zoonotic disease caused by the highly infectious pathogen Coxiella burnetii and has global distribution with important health, social and economic implications. A number of other properties and characteristics of the causative agent and disease, define Q fever as a lasting and difficult veterinary and epidemiological problem, namely: the adaptability of C. burnetii and its high resistance in the external environment; the possibility of the existence of the agent in three- and two-member parasitic systems; the availability of natural and agricultural foci of infection; peculiarities of pathogenesis in humans and animals, and the mechanisms of excretion of the pathogen into the environment; and the high susceptibility of non-immune populations of animals and people. Given that C. burnetii is included in the arsenal of bacteriological weapons as agent with potential bioterrorist threat must be borne in mind the strategic importance of this microorganism. This book summarizes and analyzes the scientific facts and developments about Q Fever researched worldwide and performed by the author to propose a system for monitoring, control and prevention covering the main necessary actions, measures and activities in the fight against this fever. There is an uneven level of knowledge of Q fever in animals and humans in various countries on the planet, while the assessment of the relevance of the problem is often ambiguous and unrealistic in terms of veterinary, medical and social and economic aspects, which can result in an incomplete diagnosis, inaccurate information about the spread of disease and lack of purposeful struggle. The scientific topics discussed include: * Biological, morphological and immunological properties of Coxiella burnetii * Diagnosis, clinical forms and manifestations, pathologic changes * Epidemiology of Q fever in animals and humans * Prevention and Control. | ||
| 545 | 0 | |a Svetoslav P. Martinov | |
| 588 | 0 | |a Print version record. | |
| 650 | 0 | |a Q fever. | |
| 650 | 1 | 2 | |a Q Fever |
| 758 | |i has work: |a Q FEVER (Text) |1 https://id.oclc.org/worldcat/entity/E39PCYffmqyw3vPQ6hGjXJhtjC |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
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